Mishonga Itsva Yekuzvimba

Entrinsic Bioscience (EBS) yakazivisa chishandiso chekuyera intestinal peristalsis iyo inogona kutungamira mukugadzirwa kwemishonga yekurapa kuvimbiswa, kusanganisira Irritable Bowel Syndrome-Constipation (IBS-C). Muongorori wepaUniversity yeFlorida Dr. Sadasivan Vidyasagar, muvambi uye sachigaro webhodhi rekambani yezano resainzi, nguva pfupi yadarika akagovera chishandiso chekuyera zvirinani peristalsis uye kupindirana kwe intraluminal pressure, kudhonzwa kwemhasuru, uye shanduko yehuwandu hwemvura pamusangano weExperimental Biology 2022 wakaitwa Philadelphia.      

Peristalsis chirongwa chekubatana chemukati memhasuru kudzvanya kunofambisa chikafu kuburikidza nemudumbu. Kunyangwe yakadzidzwa zvakanyanya, iyo yemhando yekuongorora yeperistaltic propulsion haina kunzwisiswa zvizere nekuti hapana chechokwadi chishandiso chiripo. Kushaikwa kwechishandiso kune kushomeka kuwanikwa kwezvinodhaka mumunda wekuzvimbirwa, kusanganisira IBS-C.

Vidyasagar nechikwata chake, icho chaisanganisira vaongorori kubva kuUF neEntrinsic Bioscience, vakashandisa mwenje wekutungamira, kufungidzira-mumunda pamwe nekumanikidza kurekodha kuyera net peristaltic chiitiko.

Stephen J Gatto, sachigaro uye Mukuru mukuru weEntrinsic Bioscience, akakorokotedza Anusree Sasidharan nevamwe vose vechikwata chaDr. Vidyasagar nekuramba vachizvipira mukufambisa nzira itsva dzekuongorora gwara redumbu.

"Mharidzo yechikwata inosimbisa kugona kwedu kuyera zvirinani gut peristalsis uye inotaridza nzira yeramangwana rekurapa rinogona kugadzirisa opioid-induced chronic constipation pamwe neiyo isiri-PEG-based nzira yeacute constipation uye IBS-C. Gut peristalsis abnormalities iri pakati pehuwandu hwakawanda hwemamiriro ekurapa akajairika, senge kuvimbiswa uye kuzvimba bowel chirwere. "

"Kukwanisa kushandura zvikamu zveGI uye kuongorora mhedzisiro inogona kushandura matarisiro atinoita nyaya dzeperistaltic pakuvanzika / kutora kutora," Gatto akaenderera mberi. "Maitiro akanaka aya, isu tinotarisira kuti achabvumira kukurumidza kuvandudzwa kwemishonga yedu yeRxAA yekurapa kuvimbiswa uye IBS."

Vidyasagar akapawo poster pachishandiso chaakagadzira lab yake kuyera zvirinani intestinal peristalsis uye kupindirana kwe intraluminal pressure, kudhonzwa kwemhasuru, uye shanduko yehuwandu hwemvura.

"Chikwata chedu chakagadzira nzira nyowani yekunzwisisa peristalsis uye gut mucosal mashandiro. Basa reSAA seRxAAs riri kuratidza chivimbiso sezvatinozarura nzira dzekudzivirira kusingaperi, IBS nezvimwe zvirwere zvine chokuita neGI, "akadaro Dr. William Denman, Chief Medical Advisor kuEntrinsic Bioscience. "Basa iri richiri danho rekutanga asi rinomiririra danho rakakosha mukuvandudza kwemhinduro dzezvirwere zvakawanda zvekugaya."

Entrinsic Bioscience ndeye UF yekutanga iri muUF Innovate | Kurumidza kuSid Martin Biotech muAlachua. Iyo kambani iri kugadzira zvese-zvakasikwa, glucose-isina maumbirwo ekiriniki hydration, hutano hwematumbo uye hutano, allergies, uye kuchengetedza ganda.