AMPEL BioSolutions nhasi inozivisa budiriro mune chaiyo uye yemunhu mushonga inogona kushandura nzira iyo vanachiremba vanorapa zvirwere zveganda zvinozvimba, seLupus, Psoriasis, Atopic Dermatitis uye Scleroderma. Zvakazarurwa mupepanhau rakatariswa nevezera reScience Advances, bepa rinotsanangura nzira yeAMPEL yekuvandudza muchina yekuratidza chiitiko chechirwere kubva kudhata rekutaura rinowanikwa kubva kune murwere ganda biopsies. Muedzo werabhoritari, ingori pfungwa yemakore mashoma apfuura, yagadzirira kuvandudzwa kuti ishandiswe. AMPEL yekutanga yakatarisa yaive Lupus, asi bvunzo inogona kushandiswa kune dzakawanda autoimmune kana kuzvimba zvirwere zveganda zvinobata vanopfuura mamirioni makumi matatu neshanu vekuAmerica.
AMPEL's innovative machine learning approach, iyo yagadzirira kugadzirwa sesarudzo inotsigira biomarker test, inogona kukanganisa hutano nekubvumira vanachiremba kuti vaone chikonzero chezviratidzo zvechirwere chemurwere uye kusarudza marapirwo akakodzera. Maitiro eAMPEL anotarisisa zvakakwana kuona shanduko muganda risingabatanidzwe kuitira kuti kupindira nekukurumidza kunogona kudzivirira systemic flares uye kukuvara kweganda kunoonekwa mumaronda. Kushandiswa kweAMPEL nzira yekudzidza muchina kunogona kubatsirawo makambani emishonga mukuvandudza zvinodhaka uye miedzo yekiriniki.
Varwere vane zvirwere zvisingaperi zveganda vanowanzotambura nechirwere chisingatarisirwi chiitiko chinokanganisa zviitiko zvezuva nezuva sebasa uye hupenyu hwemhuri. Sezvo zviratidzo zvisingatarisirwi zvinowanzokonzera nzendo kuenda kuEmergency Room, kukwanisa kufanotaura chirwere chinowedzera uye kubatanidzwa kwemaitiro nemaitiro eganda biopsies ane hutano hwakakosha hwehutano uye hutano hwehutano hwehutano.
Yakabatanidzwa neAMPEL's pombi yezvishandiso zvekuongorora makuru uye akaomarara ekiriniki datasets ("Big Data"), chirongwa chemuchina cheAMPEL idanho rakakosha rekuita ongororo yeganda yekutarisa chiitiko chechirwere uye kupa rutsigiro rwesarudzo pakurapa kunoenderana nejini remurwere. kutaura. Izvi zvinoshandura nzira iyo vanachiremba vanobata nayo zvirwere zveganda zvisingaperi nekushandisa ruzivo rwakaunganidzwa nerabhoritari bvunzo uye kuongororwa nemuchina kudzidza kuongorora, kuratidza iwo chaiwo mamorekuru abnormalities uye kurapa zvirwere zveganda kusati kwatanga kukuvara, kuponesa varwere kubva mukurwadziwa uye kusagadzikana kwechirwere icho. neimwe nzira inotapura zvikuru upenyu hwavo.
Makambani emishonga anoedza mishonga mumakiriniki ekuedzwa uye anotarisana nedambudziko rekunyoresa varwere vane mukana wakanakisa wekupindura kurapwa kuri kuongororwa. Kunyoresa varwere “vasiri ivo” kunogona kukonzera kukundikana kwekuedza, kazhinji zvichikonzera kukanzurwa kwekuvandudzwa kwemushonga kuenda kumvumo yeFDA iyo inogona kubatsira muboka diki rehuwandu hwevarwere. Kuongororwa kweganda kweAMPEL kuchabatsira makambani emishonga kuona varwere vangangopindura kune chaiwo marapiro, nokudaro zvichibatsira kuvandudza zvinobuda muzviedzo zvekiriniki.
Dr. Peter Lipsky, Chief Medical Officer uye Co-Muvambi, AMPEL BioSolutions: “Parizvino hapana kumwe kushanda kunogona kufanotaura nemazvo basa rehosha uye kuronga marapiro akakodzera, uye tinokurudzirwa zvikuru nebudiriro iyi yakashumwa muScience Advances. Kune avo varwere vanotambura nezvirwere zvisingaperi zveganda, hutsva hunoreva mukurapa haugone kuuya nekukurumidza. Tichitevera kuvandudzwa kwepfungwa yedu yekudzidza muchina, isu tinokwanisa kufambira mberi mukushanda nevatinoshanda navo kugadzira iyi bvunzo yeganda inogona kushandura nzira iyo vanachiremba vanogona kubatsira varwere vane chirwere cheganda chisingaperi kugadzirisa mamiriro avo nekupa kurapa kuri nani uye kwakanyatso kunoenderana nemunhu. data remurwere kwete nzira yakajairika. ”
Dr. Amrie Grammer, Chief Scientific Officer uye Co-Founder, AMPEL BioSolutions: “”Chikwata chedu chakagadzira chishandiso chinogona kushandura mabatirwo anoitwa varwere veganda. Sekambani yemishonga chaiyo, AMPEL iri kushandura paradigm yekurapa mu autoimmune uye zvirwere zvinoputika. Tinodada nekuita basa iri muVirginia uye ticharamba tichitsvaga tarenda nekusimudzira bhizinesi redu pano. "
Dr. Wright Caughman, Muzvinafundo, Dhipatimendi reDermatology, Emory Chikoro cheMishonga, uye Exec VP weHutano (Emeritus), Emory University: "AMPEL's yakanyanya hunyanzvi hwekuongorora ganda biopsy ichapa chishandiso chitsva chakanakisa chekuongorora uye kutonga kwe autoimmune uye. zvirwere zvinoputika zveganda. AMPEL iri kupa basa iri kumusangano weSociety for Investigative Dermatology kupera kwemwedzi uno. Kana AMPEL's Clinical genomic test yapihwa Certified yeCLIA, varapi vanozokwanisa kukurumidza kuona mishonga yakanakisa kumurwere wega wega uye kuwana nekukurumidza uye kwakachengeteka kutonga kwechirwere chavo.
ZVOKUBVA MUNYAYA INO:
- This will transform the way doctors treat chronic skin diseases by using the information gathered by the lab test and analyzed by machine learning to diagnose, characterize the precise molecular abnormalities and treat skin diseases before damage begins, saving patients from pain and inconvenience of a disease that otherwise drastically affects their lives.
- Paired with AMPEL’s pipeline of tools to analyze very large and complex clinical datasets (“Big Data”), AMPEL’s machine learning program is a significant step towards implementing a routine skin test for monitoring disease activity and providing decision support for treatment based on a patient’s gene expression.
- Following the development of our machine learning concept, we can now move forward in working with our partners to develop this skin test that could transform the way doctors can help patients with chronic skin disease manage their condition by offering better and more precise treatments based on individual patient data rather than a general approach.
