Curative Biotechnology, Inc. yakazivisa nhasi kuti kambani yafambira mberi mune yayo Yakanaka Laboratory Practice (GLP) toxicology kudzidza.
Chidzidzo chazvino chakagadzirirwa kuyera kushivirira, pharmacokinetics uye chero yemuno kana systemic toxicity ye reformulated metformin kana ichinge yakapihwa ne topical ocular delivery. Chidzidzo ichi chinoongororawo kugovera kwenyama yemaziso.
Iyo Yakanaka Laboratory Practice (GLP) toxicology kudzidza chinhu chinodiwa kune FDA Investigational New Drug (IND) faira.
Kushivirira kwemaziso kunosanganisira kucherechedzwa pakuita dosing, kuongororwa kwekiriniki kaviri pazuva (kuongororwa kwemaitiro / zviratidzo zvekiriniki zvakanyanya kutariswa kumaziso), kuongororwa kwemaziso neBoard-yakasimbiswa veterinary ophthalmologist maererano neyakagadziridzwa Hackett-McDonald scoring scale, uye ocular histopathology. .
Pasi peChibvumirano cheCooperative Research and Development Agreement (CRADA), National Eye Institute (NEI) uye Curative Biotechnology, Inc. ichabatana kuongorora Curative's proprietary ocular metformin kuumbwa muzvidzidzo zvekiriniki kurapwa kwepakati uye kunonoka-nhanho Age-Inoenderana Macular Degeneration. (AMD) chirwere.
ZVOKUBVA MUNYAYA INO:
- Kushivirira kwemaziso kunosanganisira kucherechedzwa pakuita dosing, kuongororwa kwekiriniki kaviri pazuva (kuongororwa kwemaitiro / zviratidzo zvekiriniki zvakanyanya kutariswa kumaziso), kuongororwa kwemaziso neBoard-yakasimbiswa veterinary ophthalmologist maererano neyakagadziridzwa Hackett-McDonald scoring scale, uye ocular histopathology. .
- The current study is designed to gauge tolerability, pharmacokinetics and any local or systemic toxicity of reformulated metformin when administered by topical ocular delivery.
- Iyo Yakanaka Laboratory Practice (GLP) toxicology kudzidza chinhu chinodiwa kune FDA Investigational New Drug (IND) faira.
