AffaMed Therapeutics, kambani yepasi rose yekiriniki yebiotechnology yakazvipira kusimudzira nekutengesa zvinoshandura mishonga, dijitari uye zvigadzirwa zvekuvhiya, nhasi yazivisa kuti United States Food and Drug Administration (FDA) yakabvisa chikumbiro chayo cheInvestigational New Drug (IND) chekuvandudza kiriniki. AM712 (ASKG712), inova proprietary bispecific biologic molecule inovhara zvose vascular endothelial growth factor (VEGF) uye angiopoietin-2 (Ang-2) yekurapa retinal vascular zvirwere.
Pasi peiyi IND, AffaMed ichakurumidza kutanga Chidzidzo chekutanga muUnited States kuti iongorore kuchengetedzeka, kushivirira, pharmacokinetics, uye kushanda kwe AM1 muzvidzidzo zvine neovascular AMD.
AffaMed Therapeutics ichangobva kupinda muchibvumirano cherezinesi neAskGene Pharma Inc. chekodzero dzakakwana dzekugadzira, kugadzira nekutengesa AM712 munzvimbo dzaimbova dzeAsia pamwe neJapan pasi rose.
"Isu tinofara kubatana neAskGene uye kugamuchira yedu yekutanga IND mvumo kubva kuFDA." Dr. Dayao Zhao, CEO weAffaMed vakati: ”Sechikamu chehurongwa hwedu hwekuChina-ye-Global innovation kusimudzira kuvepo kwakasimba kweAffaMed muChina neUS kufambisira mberi marapirwo akasiyana emisika yepasirese, chibvumirano cherezinesi ichi chinowedzera kusimbisa pombi yedu yepasi rose yeophthalmology. . Ndiri kufara kuona kukurumidza kuita kwedu zano iri kubva pakupihwa rezinesi kuenda kuUS IND kubvumidzwa uye ndinotarisira kushandira pamwe kwedu neAskGene. "
"AskGene yakazvipira kukurumidza kuunza mishonga yakachengeteka uye inoshanda kuvarwere kuburikidza nekushandiswa kwehunyanzvi hwekuita. Isu tinofara zvikuru kushanda pamwe neAffaMed kugadzira inovimbisa anti-VEGF/ANG2 bispecific molecule AMG712(ASKG712) kubatsira varwere” akadaro Mukuru weAskGene Dr. Jeff Lu: “Unyanzvi hwepasi rose hwakaitwa nechikwata cheAffaMed munharaunda yeophthalmology hwaive hwakakosha. zvakakosha kufunga nezvekubatana kwedu. Tichishanda pamwe chete, tinokwanisa kukurumidzira kusimukira kwe ASKG712 pasi rose.
Dr Ji Li, Mutungamiri weAffaMed akataura kuti: "Tinotenda kuti AM712 ine mukana wekuve yakanakisa-mu-kirasi anti-VEGF/Ang-2 bispecific biologic molecule kugadzirisa zvakanyanya zvisina kukwana zvinodiwa pakurapa pakati pevarwere vane retinal vascular zvirwere. Isu tinofara kuratidza kugona kwedu kwakasimba mukutora mvumo yeUS IND mukati memwedzi miviri mushure mekupedza chibvumirano chedu cherezinesi neAskGene. "
