Nyowani Yekukurumidza Muedzo weALS Toxin BMAA

Chibvumirano chasvikwa nhasi pakati peArlington Scientific, Utah yakavakirwa mugadziri wemakiriniki ebvunzo dzekurapa, uye Brain Chemistry Labs, isiri-yekuita purofiti sangano rekutsvaga muJackson Hole yekuvandudza nekukurumidza, nyore kushandisa bvunzo ye cyanobacterial toxin BMAA iyo yakaverengerwa senjodzi chinhu cheALS uye zvimwe neurodegenerative zvirwere.             

Chibvumirano ichi chinouya pazvitsitsinho zvechinyorwa chitsva chakakosha nemasayendisiti kuArizona State University vanogumisa kuti BMAA, muchetura unowanzo kuwanikwa mucyanobacterial blooms, unokonzera ALS, chirwere chinouraya chinouraya mutezo.

"Tichifunga nezvemakore makumi matatu nemashanu enhoroondo yeArlington Scientific mukupa makiriniki ezvehutano ezvekurapa kune vaongorori nevarapi pasi rese, tinofara kubatana neBrain Chemistry Labs kugadzira yekukurumidza lateral yekuyerera kit kuti vaone nekuvimbika. BMAA mumidziyo yemvura uye zvekudya zvemugungwa,” akadaro Ben Card weArlington Scientific. "Pave paine kudiwa kwakasimba kwenzira yekukurumidza uye yakavimbika yevaongorori, varapi, mamaneja emvura, uye vanhuwo zvavo kuti vaone kuvepo kweBMAA mumasampuli ezvakatipoteredza."

Dr. Paul Alan Cox, Mutungamiriri Mukuru weBrain Chemistry Labs, akawedzera, "Tinofara kuti tsvakurudzo yekutanga yakagadzirwa murabhoritari yedu ikozvino ichaitwa kuti iwanikwe zvakanyanya kuburikidza neArlington Scientific. Neruzivo rwavo rwenguva refu mukugadzira kits yekuongorora zvirwere, ivo vari pachinzvimbo chakanaka chekushandura tsvakiridzo yedu yekutanga kuita fomu rinogona kushandiswa. "

Kunyange zvazvo genetic ngozi zvinhu zvakatsvakurudzwa zvakanyanya, chete 8-10% yezviitiko zveALS ndeyemhuri. Zvemamiriro ekunze njodzi zvinhu zveALS zvinotendwa kuita basa rakakosha mune yasara 90-92% yemakesi ayo ari sporadic.

Masayendisiti paBrain Chemistry Labs akatanga kuwana BMAA kuti igadzirwe necyanobacteria panguva yezvidzidzo zvavo zvakakura zvechirwere cheALS-sechirwere muGuam.

Mune bepa rakaburitswa kutanga svondo rino muScience yeTotal Environment, vaongorori veArizona State University vakaongorora mapepa esainzi zviuru zana nemazana manomwe nenomwe mukuyedza kuisa zvikonzero zvinogona kukonzera ALS. Vakashandisa nzira yeBradford Hill, inova nzira yekuyera njodzi dzechirwere chinokonzera.

BMAA yakawanikwa iri yepamusoro inotsigirwa yengozi yezvakatipoteredza yeALS, uye iyo chete yezvakatipoteredza chinhu inosangana nezvipfumbamwe zveBradford Hill maitiro.

Kunyange zvazvo BMAA yakabuda kubva kuArizona kudzidza sechinhu chinonyanya kutsigirwa chinokonzera chikonzero, "BMAA haigoni kuva iyo inonyanya kukonzera ALS," Dr. Cox akanyevera. "Kunze kweGuam, kuratidzwa kweBMAA kunogona kuitika chete pakati pevanhu vanogara pedyo nemadziva ane utachiona uye nzira dzemvura kana vanosangana nemadutu eguruva remugwenga ane cyanobacteria."

Parizvino, kuyera BMAA mu cyanobacterial blooms kunoda kunyatsodzidziswa masayendisiti achishandisa michina yerabhoritari inodhura. "Tine chinangwa chekugadzira lateral flow immunoassay, kufanana nekuongorora pamuviri, iyo ichapa nzira inokurumidza uye isingadhuri yekuona BMAA nemamaneja emvura, vabati vehove, uye vanhu vanorara," anotsanangura kudaro Ben Card. "Tarisiro yedu ndeyekuti kuona nekukurumidza uye kwakaringana kweBMAA kunogona kubatsira vanhu kudzivirira njodzi dzisina basa dzeALS."